10.1136/gutjnl-2017-315734 Gut
Instead, research points to activity across multiple interconnected systems, including modulation of the nitric oxide (NO) system, upregulation of growth factor expression (notably VEGF, EGF, and FGF pathways), promotion of angiogenesis, and activation of the FAK-paxillin signalling pathway involved in cell migration and tissue organisation
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And indeed those fall under this category, but there are a bunch of other tissues for which you may want to improve metabolism and perhaps growth as well