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Generally, baseline differences were minor and not statistically significant

Notably, treatment with Fer-1, a ferroptosis inhibitor, significantly alleviated pericyte injury ( postmortem striatal brain tissue from three patients with PD exhibited elevated FTH1 and IL-8 expression, closely recapitulating the transcriptional profile of microglia in the in vitro model

N Engl J Med 377:23372348

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