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doi: 10.1002/hep.28156 4 European Association for the Study of the Liver

Obukhov AG, editor

Other factors include: Underlying cause of deficiency : Pernicious anaemia, malabsorption disorders, or dietary insufficiency may affect treatment response Medication use : Metformin and proton pump inhibitors can reduce gastrointestinal B12 absorption (though this does not affect the efficacy of intramuscular injections) Individual variation : Differences in how efficiently your body utilises the injected vitamin Adherence to treatment schedule : Missing injections or delaying maintenance doses can slow recovery Discussing these factors with your healthcare provider helps set realistic expectations for your treatment journey

doi:10.4103/2152-7806.85609

Unexpectedly, recent notable studies have suggested that excessive antioxidants increased mortality rates of cancer and cardiovascular diseases (Poljsak et al., 2013