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In half of the trials, the rule was the same as in the previous trial (Repeat trial), and in the other half, the rule switched (Switch trial) based on a pseudo-randomized sequence
That said, FDA approval is never guaranteed and depends entirely on final clinical trial outcomes, regulatory review, manufacturing readiness, and whether the FDA determines that the benefits outweigh the risks for public use
Curcumin is typically studied in concentrated extract form, which is more bioavailable than culinary turmeric used in cooking
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with age, causing low acetylcholine levels which in turn are thought to contribute to the impairment of brain function that is associated with aging