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J., & Bonnier, F

Given the first-mover commercial advantages documented in biosimilar markets (the first two to three entrants have consistently captured over 90% of biosimilar market share in physician-administered settings), the race-to-market analysis is as commercially important as the patent litigation analysis

Pratley RE et al

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Infusion of pramlintide, a human amylin analogue, delays gastric emptying in men with IDDM

Administration Injection type: Intramuscular (IM) or subcutaneous IM injection sites: Deltoid (upper arm), gluteus (buttock), or vastus lateralis (outer thigh) Subcutaneous sites: Abdomen, outer thigh, or back of upper arm Needle gauge: 25-27 gauge for IM, insulin syringe for subcutaneous Timing: Morning or early afternoon is preferred, as the energy boost may interfere with sleep if taken late in the day