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Paul and Donna are my angels in disguise
project PIE14-00005 (Flexi-Met, Instituto de Salud Carlos III, Ministerio de Sanidad, Spain)
Electrolytes and GLP-1 Medications: Why They Matter and What to Take GLP-1 (Glucagon-like peptide-1) medications, like Wegovy and Mounjaro, are powerful tools in managing appetite and promoting weight loss
CrossRef Protective effect of vitamin D on high-fat-diet-induced metabolic dysfunction-associated steatotic liver disease in mice Amal A
Includes DEXA tracking, physician consultations, and medication
Clinical trials vs real-world results What the clinical trials show The landmark SURMOUNT-5 trial published in 2025 compared these medications directly at standard maximum doses: 1 Mounjaro (tirzepatide 15 mg) produced 20.2% average weight loss Wegovy (semaglutide 2.4 mg) produced 13.7% average weight loss The 6.5 percentage point difference was statistically significant This trial used the maximum approved doses at the time (Mounjaro 15 mg, Wegovy 2.4 mg) and lasted 72 weeks
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