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Huperzine A alleviates oxidative glutamate toxicity in hippocampal HT22 cells via activating BDNF/TrkB-dependent PI3K/Akt/mTOR signaling pathway
Moreover, the iron chelator Deferoxamine inhibited RSL3/BV6-induced cell death significantly, however, it could not rescue cell death by Erastin/BV6, indicating that RSL3/BV6-, but not Erastin/BV6-mediated cell death depended on iron
Renal protection has been observed in models of acute kidney injury, with improved function markers and reduced tissue damage
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