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Causing fat loss while maintaining muscle mass would therefore be an attractive feature of a novel therapeutic (Versanis bimagrumab may be differentiated here)
Increased evidence suggests that metabolic reprogramming is closely related to the progression of diseases and drug resistance
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Lancet 406 , 149162 (2025)
In OA, contrast-enhanced MRI, ultrasound-based assessment of synovitis, and synovial fluid or serum biomarkers of fibrosis and inflammation could be leveraged to directly assess changes in synovial fibro-inflammatory pathology
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