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Retatrutide Side Effects Common: Nausea: ~43% at 12mg (TRIUMPH-4) Diarrhea: ~33% Vomiting: ~20% Dysesthesia: 20.9% at 12mg (abnormal skin sensations unique to retatrutide) Discontinuation due to adverse events: 11.3% (TRIUMPH-1, general obesity) / 18.2% (TRIUMPH-4, osteoarthritis population)
If emotional eating has been a long-standing pattern, working with a therapist or counsellor who specialises in eating behaviours is worth considering
It also plays an important role in supporting fat metabolism
The therapy led to weight loss in a mouse model of obesity by decreasing food intake and increasing energy expenditure [100]