Fascinating case study
Medical Science Monitor (2010)
Alanine and pyroglutamic acid were significantly associated with an alteration of glutathione metabolism
[,] Yang et al ., 2019, [] found that NAC did not improve PANSS, while Pyatoykina et al ., 2020, [] observed a significant decrease in negative PANSS and total PANSS compared with placebo
While research is lacking on risks to people with eczema who use glutathione, topical products can cause allergic reaction, irritation, stinging, or redness, especially if they contain alcohol, fragrances, or preservatives
Despite low CNS penetration, some studies report detectable levels in the brain, supporting its potential for systemic biological effects without significant accumulation (Jzwiak et al