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In the absence of a definitive cause for IBD, and hence a cure, novel and often nuanced aspects of disease pathophysiology continue to be uncovered

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According to the NIH Office of Dietary Supplements, B12 plays a key role in: Making red blood cells and preventing megaloblastic anemia Maintaining healthy nerve function and the myelin sheath that protects nerves DNA synthesis Supporting brain function and preventing cognitive decline Converting food into energy (cellular metabolism) Because B12 is found almost exclusively in animal products meat, fish, dairy, and eggs certain groups of people are at much higher risk of deficiency than others

Now when patients ask if they should push through, I tell them: "Your body will go as fast as it can go

The gut microbiota of IBD patients exhibits a trend towards reduced diversity, manifested explicitly by a decrease in the abundance of commensal Clostridia and a significant enrichment of pathogenic bacteria