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In intestinal organoids, mitochondrial copy number increases during differentiation, and mitochondrial electron transport chain activity is required for the initiation of crypt formation 55
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Open communication with healthcare providers, realistic weight loss expectations (0.5-1kg weekly as per NHS guidance), and attention to overall wellbeing rather than rapid results will optimise both metabolic and reproductive outcomes during weight loss injection therapy
Lancet (2019) 394(10192):3950
Understanding these potential adverse effects helps set realistic expectations during treatment initiation
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