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Although saikosaponins have poor intestinal absorption due to their large molecular mass, high molecular flexibility, and high hydrogen-bonding capacityfeatures that limit membrane permeabilitycertain subtypes (saikosaponin a, b1, d, g, c) have been shown to exhibit relatively high bloodbrain barrier permeability in a microdialysis experiment, making them potential antidepressants (Yu et al., 2012

Many of these are not being done across the country

doi: 10.1136/jmedgenet-2021-107965 51 ChiA.LogroscinoG.TraynorB

This is especially important if your Mounjaro was prescribed for type 2 diabetes stopping affects blood sugar management, not just weight