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mTOR regulates phosphorylation of p70 S6 kinase (p70S6K) and eukaryotic initiation factor 4E (eIF4E) binding protein 1 (4E-BP1), the two best-characterized downstream effector molecules of mTOR 10
Morales-Borges RH, Gonzalez MJ, Duconge J, Minich DM
It has been extensively studied for its role in sleep regulation, neuroendocrine balance, and stress adaptation
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Our study may prove that these endpoints are not suitable for irritancy testing of copper compounds in a monolayer HaCaT assay
10.3892/ol.2015.3943 47 HanahanD.WeinbergR
