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The higher power, the higher the discharge rate (C-rate)

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Yes this is exactly why the dose escalation schedule exists

Injection site reactions With subcutaneous administration, redness, itching, or irritation at the injection site may occur

Calabrese V, Cornelius C, Dinkova-Kostova AT, Calabrese EJ, Mattson MP: Cellular stress responses, the hormesis paradigm, and vitagenes: novel targets for therapeutic intervention in neurodegenerative disorders