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While they can be uncomfortable, they usually improve within a few weeks as your body adjusts

All of these mice have a C57/BL6 background

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Both injections should be done during the same dosing session

Individuals have reported hair loss when taking these drugs, as well as aspiration (when food or liquid enters the airway) when sedated for surgery, likely due to the delay in stomach emptying caused by the drugs

Those with higher starting weights or metabolic conditions may require dose escalation to achieve proportional progress