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10.1053/ajkd.2001.27408 22 HagbergH.MallardC.RoussetC

In this condition, parathyroid hormone levels are elevated

Nrf2 depletion in macrophages leads to increased foam cell formation, increases the M1 inflammatory phenotype with enhanced expression of pro-inflammatory monocyte chemoattractant protein-1 and interleukin-6, and aggravates atherosclerosis (244, 245)

They work by blocking glucose reabsorption in the kidneys, causing excess glucose to be excreted in urine

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