Quick Takeaways AOD 9604 directly targets fat cell metabolism without affecting appetite or growth hormone pathways Tirzepatide works primarily through appetite suppression and glucose control as a dual GLP-1/GIP agonist Tirzepatide has robust human clinical trial data showing over 20% body weight reduction
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The use of NNMT inhibitors as a potential obesity treatment has been investigated preclinically 8,9,13 , and observational clinical data suggests that increased NNMT expression and activity correlate with increased incidence of Type 2 diabetes (T2D) and risk of obesity, respectively 10,11
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