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Insulin resistance and PCOS: Patients with severe insulin resistance or polycystic ovary syndrome (PCOS) may have a more complex metabolic profile that requires additional intervention beyond GLP-1 therapy alone

Increase dietary fiber gradually (vegetables, whole grains, legumes) Gentle physical activity, such as a 2030 minute walk, stimulates gut motility

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Immune cells might also interact with stromal cells, playing a pivotal role in driving pro-inflammatory and pro-fibrotic activities (4)

Scenario B: The "Normal" TSH but Persistent Fatigue "My GP checked my TSH and said it was normal, but since starting my weight loss journey, I feel more exhausted than ever