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doi: 10.1016/j.xinn.2024.100722 21 TrapnellCCacchiarelliDGrimsbyJPokharelPLiSMorseMet al

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Efforts to refine and isolate salicin and salicylic acid took place throughout the middle- and late-19th century, and was accomplished by Bayer chemist Felix Hoffmann (this was also done by French chemist Charles Frdric Gerhardt 40 years earlier, but he abandoned the work after deciding it was impractical)

Consistency is often considered one of the most important aspects of long-term lip maintenance