5) Phase 3 CagriSema awaits FDA approval 20262027 as first dual-agonist amylin+GLP-1 medication
We have previously identified a compound YMU1, an inhibitor of thymidylate kinase (TMPK), which increased doxorubicin sensitivity of cancer cells by causing DNA repair toxicity 19,20
Stearoyl CoA desaturase regulates ferroptosis in ovarian cancer offering new therapeutic perspectives
Post-translational modifications, especially those in the DNA binding domain of FOXO4 protein, appear to modify its functionality as a transcription factor and regulation of pathways such as apoptosis, cellular senescence, insulin signaling, and senescence
Most injections produce no bleeding
We established a D-galactose-induced aging model in randomly selected male and female mice through intraperitoneal injections of D-galactose (200 mg/kg/day, MCE, HY-N0210), starting at 8 weeks of age for 8 weeks