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The decrease in myocardial contractability and heart rate, as well as the reduction in blood pressure, produced by atenolol generally lead to a reduction in myocardial oxygen consumption which accounts for the effectiveness of the drug in chronic stable angina pectoris
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Selected references Aryl Sulfonamide-Substituted 5-Amino-1-methylquinolinium Derivatives as Potent and Selective Inhibitors of Nicotinamide N-Methyltransferase (NNMT) - PubMed 2021 Nicotinamide N-methyltransferase: At the crossroads between cellular metabolism and epigenetic regulation - PubMed 2021 Nicotinamide N-methyltransferase inhibition mitigates obesity-related metabolic dysfunction - PubMed 2024 Ordering Add this item to your cart, submit your shipping details at checkout, and wait for your order confirmation
This is harder to quantify but worth noting
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