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Clinical trials show patients typically lose 15 to 25% of their body weight with consistent use alongside lifestyle changes
"Triple-Hormone-Receptor Agonist Retatrutide for Obesity." NEJM 2023;389:514526
Because of the differences in product half-life and therefore dosing interval, GLP-1 RAs can be classified as short- or long-acting [6]
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Escalating to higher doses too rapidly increases side effects without improving outcomes
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