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Curcumin and its metabolites undergo further metabolism in the liver before being excreted into bile or distributed to tissues or kidneys via systemic circulation (92, 121)

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[6] [9] In addition to the UGA-codon, a cis-acting element in the mRNA, called SECIS, binds SBP2 to recruit other proteins, such as eukaryotic elongation factor selenocysteine-tRNA specific, to form the complex responsible for the recoding process