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Historically, chloroquine and hydroxychloroquine have been utilized to induce oxidative stress in order to kill malarial parasites [9, 10, 53]

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Despite these being isolates from patients, only a few strains caused cytotoxicity, reflected in release of the cytoplasmic enzyme lactate dehydrogenase (LDH), of A-431 vulvar epithelial cells in vitro (Fig

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