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BMC Cancer 23:1044

C.SugiyamaH.YoungA

Uncoupled endothelial NOS, nicotinamide adenine dinucleotide phosphate hydrogen (NADPH) oxidase, xanthine oxidase, and mitochondrial electron transport are the main sources of ROS

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Hydrazone linker Hydrazone, an acid-labile group, is used as a cleavable linker that releases free drug through hydrolysis once an ADC is transported to acidic endosomes (pH 5.06.0) and lysosomes (pH about 4.8) (Fig

Vasireddi N, Hahamyan H, Salata MJ, Karns M, Calcei JG, Voos JE, Apostolakos JM