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This unique sequence allows DSIP to be highly resistant to degradation, making it stable at room temperature and capable of crossing the blood-brain barrier
This usually occurs when theres not enough sulfur group (-SH) available for detoxification, leading to increased oxidative stress
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1 The observed beneficial effects were obtained within the specifically overstimulated or damaged dopaminergic, serotoninergic, GABAergic and opioid systems
although both shorter and longer linkers have been reported, it still seems empirical and optimization is required for each pair of ligase and target protein, since it is likely that optimal linker identity will vary for different proteins targeted
This translates to a relative reduction in liver fat by 37%, indicating a possible benefit in lowering liver fat accumulation
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