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Conditions such as atrophic gastritis (thinning of the stomach lining), Pernicious anemia (which makes it harder for your body to absorb Vitamin B12), Intestinal diseases such as crohns disease, celiac disease, bacterial growth and immune system disorders such as Graves disease or lupus can lead to Vitamin B12 deficiency in the body

At a preclinical level, hyponatremia has been associated with reduced cell adhesion and increased proliferation in cancer cell lines (322)

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Borner T, Geisler CE, Fortin SM, et al