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Stronger cardiovascular data: The SELECT trial provides robust evidence for cardiovascular protection
In vitro and ex vivo uptake of glutathione (GSH) across the intestinal epithelium and fate of oral GSH after in vivo supplementation
In peptide production (GMP, non-GMP), pGlu formation is a common cause of unexpected early-eluting peaks in HPLC, charge heterogeneity in CEX, or ambiguous mass shifts during MS-based QC
Research shows that resuming GLP-1 therapy before significant metabolic decline occurs prevents this downward spiral and restores insulin-stimulated glucose uptake more quickly
Phase 2 trials are those where the drug has some data showing safety in humans, but where further human data is needed on drug effectiveness
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