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This augmented weight loss with retatrutide is hypothesized to be partly due to its glucagon receptor agonism, which may increase energy expenditure in addition to the appetite suppression and delayed gastric emptying effects shared by GLP-1 and GIP agonism

Once opened, Ozempic pens remain effective for 56 days (8 weeks) after first use, whether stored in the refrigerator or at room temperature up to 86F

Similar to the clinical data, all three GLP-1 analogs tended to reduce skeletal muscle mass

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After that or for maintenance doses, it's $349/month