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Before mutagenesis, the D39 strain had a previous passage in mice, as described [19]
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(2019) discovered that the inactivation of 12-LOX inhibits TP53-mediated ferroptosis and abrogates TP53-dependent inhibition of tumor growth, indicating that 12-LOX is vital for TP53-dependent cancer suppression
Colocalization of the Wnt pathway and GPX2, as well as the regulation of GPX2 through Wnt signaling, suggest that GPX2 plays a role in the continuous self-renewal of the intestinal epithelium and thus in the homeostasis of the intestinal mucosa (Prez et al., 2017)
Cell Death Differ 2009
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