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PLoS One 10 , e0138505 (2015)
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Glutathione protects and cleans up
Mechanism of N-dealkylation involves oxidation of - carbon to generate an intermediate carbinolamine which rearranges by cleavage of C-N bond to yield the N-dealkylated product and the corresponding carbonyl of the alkyl group (a primary alkyl is transformed to aldehyde and a secondary alkyl to ketone)
Herbal medicine: biomolecular and clinical aspects , 2nd edition
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