The flagship trial STEP-1 (published in NEJM , 2021) found a mean weight reduction of ~14.9% of body weight with semaglutide 2.4 mg vs ~2.4% with placebo over 68 weeks ( [12] )
Data sources We retrieved data from Danish nationwide registries including the Danish Cancer Registry [17], the Danish National Prescription Registry [18], the Danish National Patient Registry [19], the Danish Civil Registration System [20], the Danish Pathology Register [21] and socioeconomic registries at Statistics Denmark [22, 23]
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