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Figure 12 Based on experimental results, a 24-h incubation with 1 mM FFAs was selected to induce the NASH cell model, with 1 M and 2 M THC used as low and high doses, respectively

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Adiponectinanother hormone synthesized by adipose cellsappears to reduce cellular insulin resistance and to protect blood vessels from inflammation and atherosclerosis

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cohort study, the 2-year discontinuation rate for GLP-1 receptor agonists was 64.1% among people with type 2 diabetes mellitus, driven by factors such as older age, low income, gastrointestinal adverse events, and insufficient weight loss [115]