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This acts on centers of the brainstem such as the nucleus tractus solitarius and the area postrema, which, in turn, upregulate the hypothalamus to release hormones which suppress the appetite, such as gastrin and cholecystokinin

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Artemisinin is a naturally occurring compound with demonstrated P15.10: a) In chapter 16 we will learn how ascorbate (vitamin C) acts as a 'radical scavenger' antioxidant to protect our cells from damage by free radical species

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The NHS notes pain and itching at the injection site as common and self-limiting