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There are also two autosomal recessive cytochrome b -positive forms of CGD identified as cytochrome b -positive CGD type I and type II

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Formate (C1) not only fuel T-cell purine synthesis and enhance antiPD-1 in vivo, but also promote tumor invasion and metastasis in some cases [72, 74]

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While glutathione supplementation is generally considered safe and well-tolerated, some individuals may experience mild side effects such as stomach upset or allergic reactions

Baseline HbA1c in these studies varied from 8.3 to 9.3% (6778 mmol/mol)