Therefore, the observed suppression of cuticle-related genes in neonicotinoid exposed, viruliferous BLHs may reflect a strategic shift toward metabolic detoxification mechanisms more suited to counteracting directly ingested xenobiotics, however whether this mechanism is conserved across other systems remains unclear, and further work is needed to confirm its broader relevance
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Experimental systems assess receptor response, binding behavior, and dosedependent activity
Neurosci Lett (2017) 636:12733.10.1016/j.neulet.2016.10.054 32 JornayvazFRShulmanGI
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May interact with several other drugs including other medications used for weight loss (including other prescribed medications, over-the-counter preparations, or herbal supplements), antidepressants, antipsychotics, antidiabetic drugs, and other central nervous system stimulants