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Interestingly, unlike other MAPKs, such as ERK1/2 and JNK1/2, it has been shown that p38 phosphorylates NRF2 and promotes its association with KEAP1, thereby preventing its nuclear translocation

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In addition to its HSA-mediated pharmacokinetic extension, albiglutide exhibits enhanced stability against enzymatic degradation by DPP-4

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