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Discussion This multicenter phase 3 trial evaluated the glucagon receptor/GLP-1R dual agonist survodutide in participants with obesity and at-risk MASLD as determined by MASLD and evidence of liver inflammation and/or fibrosis using NITs or liver biopsy-confirmed MASH

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Meanwhile, the skin barrier can become thinner when the body's immune system and metabolism changes

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When oestrogen levels are too high, it can disrupt the delicate hormonal interplay that governs the menstrual cycle, leading to irregular or absent periods, heavy bleeding, and painful cramps

After matching, the cohorts included 17,920 pairs of individuals with T2D and 4234 pairs of individuals with T2D plus ASCVD (Online Supplementary Fig