Regulatory enforcement around compounded GLP-1s has been a moving target, and new branded entrants tend to increase scrutiny, not decrease it
DPP (Dipeptidyl Peptidase)-4 inhibitor attenuates ang II (Angiotensin II)induced cardiac hypertrophy via GLP (Glucagon-Like Peptide)-1dependent suppression of nox (nicotinamide adenine dinucleotide phosphate oxidase) 4-HDAC (histone deacetylase) 4 pathway
(The third, Foundayo, just got FDA approval in April, so its too new for spending data.) In 2024, Medicare spent over $19.3 billion on Ozempic and Mounjaro, according to gross spending data from CMS
Founded in 1876, Lilly employs an R&D staff of nearly 10,000 people across seven countries
Risks include inaccurate dosing, contamination, and poor storage
The effects of exenatide and metformin on endothelial function in newly diagnosed type 2 diabetes mellitus patients: a case-control study