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The primary reason GLP-1 medications can make you gassy relates to their effect on gastric motility
How do you know it's going to be safe? The truth is that these drugs have been evaluated in animals and patients for over 18 yearswe know a lot about them
Cell Signal 31, 112123
5,6,7 GLP-1 is a peptide produced by the cleavage of proglucagon, mainly synthesized in the intestinal mucosal L-cells, pancreatic islet -cells, and neurons in the nucleus of the solitary tract
Interestingly, the microbes deamidate NAM into NA, therefore bypassing salvage
It deserves medical oversight
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