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Combination with Metformin or Metformin with Sulfonylurea In a 30-week, open-label trial (NCT02128932), 1089 patients with type 2 diabetes mellitus were randomized to semaglutide 0.5 mg once weekly, semaglutide 1 mg once weekly, or insulin glargine once daily on a background of metformin (48%) or metformin and sulfonylurea (51%)

By doing what GLP-1 does, Semaglutide makes you less hungry, helps your body make more insulin, and slows down how fast food leaves your stomach

This includes a focus on whole foods, such as lean proteins, whole grains, vegetables, and fruits

Second, metabolic/bariatric surgery has been proven to be the most effective treatment in terms of weight loss and improvement in all associated comorbidities

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Supplementary material The Supplementary material for this article can be found online at: References 1 AbediniT.HosseyniR.GhannadiF.MoghaddamH