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Can AOD-9604 raise IGF-1 or insulin levels
A person will continue to receive intramuscular vitamin B12 injections, or a doctor may suggest high dose oral vitamin B12 supplements
IGF-1 possesses both, GH-like actions and insulin-like actions, whose effects in vivo depend on the dosage, length of treatment, and even route of administration [134, 135]
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Later work examined NNMT inhibition combined with dietary changes in obese mice, reporting reductions in body weight, fat mass, and hepatic fat, alongside shifts in gut bacterial populations
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![Change in body weight with semaglutide 2.4 mg: STEP trials [95–98]](https://www.researchgate.net/publication/377114282/figure/fig2/AS:11431281215640943@1704338910350/Change-in-body-weight-with-semaglutide-24mg-STEP-trials-95-98.png)
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