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Note that our body is not very efficient at absorbing vitamin B12 from supplements, so it's better to stay on the safe side by aiming to consume well over the minimum recommended amount, rather than taking a little less or sticking to the RDI

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Most research protocols don't require accounting for overfill at the individual-dose level

Here are some common causes: Dietary deficiency, mainly in vegans and vegetarians Pernicious anemia, an autoimmune issue with intrinsic factor production Gastric disorders, like atrophic gastritis or gastrectomy Malabsorption conditions, including Crohns disease and celiac disease Certain medications, like proton pump inhibitors and metformin Signs and Symptoms Requiring Medical Intervention Its important to know the signs of vitamin B12 deficiency

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