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Of note, blood NAD metabolites were changed in all studied diseases, except for prostate cancer, while glutathione metabolites demonstrated alteration only in cancers (Fig
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In particular, long-term use of non-steroidal anti-inflammatory drugs (NSAIDs) can cause gastric mucosal damage as they can inhibit mitochondrially encoded cytochrome C oxidase I (MT-CO1, also known as COX-1) and block its protective effect on gastric mucosa
Hangauer MJ, Viswanathan VS, Ryan MJ, Bole D, Eaton JK, Matov A, et al
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