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Single GIP receptor agonists also reduced the activation of glia in AD models [173, 174] and PD animal models [119, 154, 155]

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Another patient may lose a modest amount of weight but have a major improvement in blood pressure, A1C, mobility, or sleep apnea symptoms

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FDA approved Mounjaro for Type 2 Diabetes in 2022, and later for weight loss under the brand Zepbound in Nov 2023 (US)