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This should not be attempted without qualified provider oversight
Tesamorelin, because it stimulates real growth hormone release, produces the metabolic effects associated with elevated GH including measurable IGF-1 increases and monitoring requirements for glucose metabolism in clinical settings
Importantly, B 12 supplementation generally relieved the upregulation of these genes, in support of the idea that limiting B 12 levels were driving the Met restriction in vivo
Linden A, Hansson L, Andersson A, Palmqvist M, Arvidsson P, Lofdahl CG, Larsson P, Lotvall J
[PMID: 38355887]
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