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In the retatrutide Phase 2 trial, the sex difference was even more pronounced
Nih.gov
Saibal K Biswas, Danny McClure, Luis A Jimenez, Ian L Megson, Irfan Rahman - Curcumin induces glutathione biosynthesis and inhibits NF-kappaB activation and interleukin-8 release in alveolar epithelial cells: mechanism of free radical scavenging activity - Antioxid Redox Signal - Jan-Feb 2005
These are among the strongest results seen in any anti-obesity medication trial to date
They drank 32-48 oz of fluid per day (below the recommended 64+ oz), often relying on coffee or diet soda rather than water
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