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For the most part, the treatment is an excellent option if one wishes to reduce significant amounts of fat, as a person can lose 12 percent of fat by week 28

Possible side effects include nausea, constipation, diarrhea, reflux, decreased appetite, or fatigue, especially during dose changes

Key objectives include determining long-term safety, identifying patient subgroups most likely to benefit, clarifying effects across HF phenotypes, and assessing patient-centered outcomes such as quality of life, functional status, and hospitalization burden

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