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Therefore, given the association with improved nutritional status under semaglutide treatment, this GLP-1RA could be explored in other obesity-related conditions, including fatty liver disease, dyslipidemia, hypertension, and potentially even cancer
A 2024 study published in JAMA Ophthalmology found that patients prescribed semaglutide had a higher observed risk of NAION compared with patients using non-GLP-1 medications for diabetes or weight loss
While this may be seen as a beneficial side effect for some patients, especially those who are overweight or obese, significant weight loss should be monitored by a healthcare provider
GLP-1s were prescribed almost exclusively for Type 2 diabetes until the FDA approved Wegovy for obesity in 2021
Firefly luciferase activity was measured and normalised to the control Renilla luciferase activity
Blood sugar improvements can be detected within 2-4 weeks
